Rheumatoid arthritis (RA) is a disease that affects the joints of the body, most commonly the joints of the hands, feet, wrists, elbows knees and ankles.
It is estimated that around 1.5 million people in the US have RA, and the disease is almost three times as common in women than men.
Current treatments for RA include non-steroidal anti-inflammatory drugs (NSAIDS), corticosteroids and JAK inhibitors.
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Studies show that tea may have anti-inflammatory properties. In lab studies, Case Western Reserve University researchers in Cleveland showed EGCG (a substance in green tea) may halt #arthritis progression by blocking interleukin-1, a pro-inflammatory cell, from damaging cartilage.
Salah-uddin Ahmed, of the WSU College of Pharmacy note in a study, that the compound EGCG may be a promising alternative to current treatments for RA.
EGCG is a chemical compound that belongs to a class of flavanols known as catechins. It is most abundant in #greentea and the dried leaves of white #tea, and the compound is known to have anti-inflammatory properties.
The researchers found that EGCG reduces the activity of TAK1 - a key signaling protein through which pro-inflammatory cytokines transmit their signals to trigger the inflammation and tissue damage found in RA.
What is more, the team says that EGCG reduced inflammation in RA without interfering with other cellular functions - unlike some current medications for the disease.
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